Tuesday, 23 December 2014

I'm part of the Lynch Mob

and what it really means...

Tuesday 23rd December 2014


This photo is in the box. Because it represents me.

I have Lynch - hypermethlyation of the MLH1 promoter gene to be exact. Yep, I didn't have a clue either.. here is a quote... 


Clinical Information

Hereditary nonpolyposis colon cancer (HNPCC), also known as Lynch syndrome, is an inherited cancer syndrome caused by a germline mutation in 1 of several genes involved in DNA mismatch repair (MMR), including MLH1, MSH2, MSH6, and PMS2. There are several laboratory-based strategies that help establish the diagnosis of HNPCC/Lynch syndrome, including testing tumor tissue for the presence of microsatellite instability (MSI-H) and loss of protein expression for any 1 of the MMR proteins by immunohistochemistry (IHC). It is important to note, however, that the MSI-H tumor phenotype is not restricted to inherited cancer cases; approximately 20% of sporadic colon cancers are MSI-H. Thus, MSI-H does not distinguish between a somatic (sporadic) and a germline (inherited) mutation, nor does it identify which gene is involved. Although IHC analysis is helpful in identifying the responsible gene, it also does not distinguish between somatic and germline defects.
Still not sure? Yeah, me too and I have had a couple of years to digest this. Basically Lynch Syndrome (LS) is a rare condition that runs in families. Conditions that run in families are known as familial or hereditary.
LS is named after the doctor who discovered it.
Lynch syndrome is the most common cause of hereditary bowel cancer. However, fewer than 5 in 100 (5%) of all bowel cancers are linked to LS. 
People with LS also have an increased risk of developing other cancers. In women, there is a higher risk of womb (endometrial) and ovarian cancers. Other cancers that can occur in people with LS include stomachpancreassmall bowelureter and renal pelvis cancers.
Knowing about risk and having regular screening may help prevent some cancers. It may also help others to be found in the early stages, when they're more likely to be curable. So I get monitored when I feel I need it.  I don't get monitored as much as I would like, but that is because I am neurotic! But whilst at first I felt like I had been given a death sentance, I actually realise it is a life gift.  I am only too aware how quickly life can be snatched away, and serious illnesses can take years to recover from, so every day should be special. 
 You never know what personal demons people are facing, so you never know how your kindness can change their lives.  It's nice to be nice, it makes other people be nice, and one day, hopefully the whole world will join in. 
Kids - be kind, be happy, look after your bodies they are precious. And look after each other 
x

Friday, 6 June 2014

The Granddad that got blown up in a tank...


On the 70th anniversary of D Day, we will remember them.

6th June 1944

World War II (WWII or WW2), also known as the Second World War, was a global war that lasted from 1939 to 1945. 

My Granddad was deployed as part of the D Day Invasion -  among 100,000’s of other soldiers crossing the channel to land of the shores of Normandy at the start of the drive to Berlin.  Intelligence reports suggested that the Normandy region was less well defended than the area around Calais. The length of the sea crossing made it an unlikely landing spot for the Allies - this is what the Allies hoped that the Germans would think.

I always knew that Granddad was involved and part of the invasion - he was proud of what he did for his country and quite rightly so.  Growing up I was aware that he supported the Normandy Veterans Association whenever he could - going on marches, parades and also talking at schools. I'm not sure what he said when he went to schools, because he never gave me, my brother Pete, or cousins Vikki and Richard, much detail about it. 

I remember he taught me how to do the Sherman tank salute (hold your hand, palm forward, against your forehead, just above the right eye - he always gave me a cheeky finger wiggle too, but pretty sure that was not part of the actual salute!)

I knew his tank was attacked, but again, my knowledge was pretty limited, and when I asked my mum what she knew it seemed hers was too. Those few days of his life were never really discussed. 

I lost my grandparents within months of each other and it was a sad time for my family. Granddads funeral was a military funeral, very emotional and there was even pride in his last goodbye to the world he so bravely defended. It was only many years later that I discovered that he had done an interview with the Imperial War Museum about his experience and so I went to go and listen to the archives. A great and interesting day, and emotional from the moment I heard that most familiar voice that had sung to me as a child and spoken caring words as I grew into adulthood. He visited Normandy often and had many friends there. A father and daughter came to England for his funeral and stayed with my Uncle Steve and Auntie Sue. The night before the funeral we all gathered at my grandparents house and they joined us. He did not speak much English so his daughter translated a letter he had written. He was thanking my granddad for all that he did to free them and us and to give us all the lives we now live - he was thanking him for having such strong and brave comrades that did not survive. He was thanking him for saving his life. With that line (most of us in tears at this point) he pulled out a little package. It was a small union jack flag folded up. He carefully unfolded one of the sides and showed us some earth. Earth that he had gone and collected from the graves of my granddad's tank colleagues who died in action and are buried in Aromanche - so that he could walk into the next life with these men by his side. 

When leaving the archive room, the man asked if the Mabel Tomalin interview was of interest... Was it?! I never knew my Nan had done one, and here i was listening to her telling the Poole stories of what happened to those keeping the country going. Amazing.

Just because we don't always talk about things we have done and experienced, it doesn't mean we haven't had our own hardships to face.  You never know what troubles someone may have in their life - therefore kids, be nice to everyone - you may just make their day.

Roy Ernest William Tomalin's audio can be heard on this link. 
http://m.iwm.org.uk/collections/item/object/80018709
Mabel Irene Tomalin's audio can be hear on this link
http://m.iwm.org.uk/collections/item/object/80018708

D Day - what happened... 

4.00Dwight Eisenhower gave the go-ahead for the invasion. The plan drawn up expected 132,715 troops to be landed on five beaches with 23,400 paratroopers to be dropped further inland. 6,483 ships were involved.
In case the invasion failed, Eisenhower prepared a statement that said:
"Our landings in the Cherbourg-Harve area have failed to gain a satisfactory foothold and I have withdrawn the troops. My decision to attack at this time and place was based on the best information available. If any blame or fault attaches to this attempt, it is mine alone."
22.00Five fleets of assault ships left their English port bases.
"We slipped anchor and headed into the Channel to overtake the grey columns of troops transports and landing craft, which now stretched to the horizon and beyond. They filled the scene as far as the eye could see. Overhead, the sky was filled with an aerial armada of bombers." 
John Gough, radio operator on board a destroyer.
22.56Six gliders took off from Tarrant Rushton, Dorset, for Pegasus Bridge at the eastern end of the beaches.
"No smoking till we were airborne; so to ease the tension we sang para songs to the tune of 'Knees Up Mother Brown', the end of the chorus going "I'll always keep my trousers on when jumping through the hole." I wondered if that might be true that night.
Sgt Edgar Gurney, 5th parachute Brigade
June 6th
00.16Three gliders landed just 30 meters from Pegasus Bridge. Commandos led by Major John Howard captured the bridge.
"We were coming in at 90 mph on touchdown. I suppose that really was the most exhilarating moment of my life. I could see the bridge tower 50 yards from where I was standing. Above all, the tremendous thing there was that there was no firing at all. We had complete surprise, we had caught old Jerry with his pants down."
Major John Howard
00.30The Café Gondreé by Pegasus Bridge is the first building to be liberated in France. Allied troops there were given champagne by the owner.
"Inside (the café) I saw a small French girl, ashen-faced and scared to hell. I gave her my bar of chocolate but she still did not smile."
Albert Gregory, medic.
01.00American paratroopers of 82nd and 101st Airborne make night jumps into the Cherbourg Peninsula at the western end of the beaches. Because of the cloud, a number missed their target and drowned in flooded swamps.
02.45Men began to climb down from their ships into their landing craft.
"The landing craft was rolling in every possible direction; the sea-sickness pills had failed. Lying still only made one feel worse."
Eric Broadhead, Durham Light Infantry heading for Gold Beach.
04.30St. Mère-Eglise was the first French town to be liberated. 
"(American) paratroopers began jumping out by the hundreds. I saw one paratrooper land in the road but a German killed him before he could get untangled from his parachute. Another (paratrooper) was as killed near me. I will never forget the sight."
Raymond Paris, resident of St. Mère-Eglise
05.30Naval bombardment of the shore began. By 06.00, aerial bombing of German fortifications at Omaha andUtah started.
"As we reached Omaha beach, all 40 aircraft dropped their bombs. More than 100 tons of bombs exploded in a few seconds. This was the only mission over Europe when I felt the concussion of our own bombs."
Henry Tarzca, on a B-17 of 8th Air Force
06.30American forces landed at Omaha and met stiff opposition. They suffered heavy casualties. 'Swimming' tanks, on which the Americans had placed great faith, sank out at sea due to the unexpected swell and because they were landed too far out.
06.31American forces landed at Utah. The landing craft landed a mile south as a result of the tide, but the landings were a success.
07.10US Rangers  (US Army 2nd Ranger Battalion) started an assault on Pointe du Hoc.
07.25British landings began on Gold Beach. The success of the landing was aided by 'swimming tanks' (Duplex Drive Sherman tanks) that did get ashore.
British troops landed on Sword Beach. Commandos led by Brigadier Lord Lovatt joined up with the men at Pegasus Bridge.
07.30Canadians landed on Juno Beach, again aided by DD Sherman tanks. 
"The German machine gunners in the dunes were stupefied to see a tank emerge from the sea. Some ran away or just stared, mouths wide open."
Sgt Leo Gariepy
09.15General Omar Bradley thought about abandoning the landing at Omaha because extra men could not be landed as the beach and sea was crammed with dead bodies.
12.00The Americans had made successful advances up Omaha Beach aided by gunfire from small naval vessels that sailed as close to the beach as they could.
22.07A ten-miles deep and sixty miles wide bridgehead had been established

Wednesday, 12 March 2014

Understanding Crocodiles

Meeting inspirational people. Then buying their mouse mat.

January 2006





Travelling to Australia had always been a desire of mine, but due to the expense I just never thought it would happen.  I'd started saving but it would take a long time as I was already trying to pay off debts at the time. Any sensible person will tell you - there is no point having savings if you have debts!

My trip became reality when my maternal grandparents funded it. I would much rather that they were here to enjoy, but the sad situation was that they died within 48 days of each other in 2005, leaving all of the grandchildren (in age order you have cousin Vikki, brother Peter, cousin Richard and then me - all 1 year apart) some money to spend on something we really wanted to. This for me was to see Australia. My grandparents helped me realise a dream, I wish they had been around to see it. I still talk to them though, no one is ever truly gone if they are in your heart. 

So off I flew, across the world,via Shanghai, (an experience!)
 and spent time with my university friends Clare (who was living in Sydney) and Anna (who was also visiting Australia) - two of those dearest friends that you know will be in your life for a long time (hold on to those people). Christmas and New Years was spent in the company of these amazing girls and many good times, including a trip to Hunter Valley to taste wines... ah perfect!

I then made my way up the coast to Port Douglas in Cairns, to realise one of my bucket list items of scuba diving the Great Barrier Reef, then made my way down to Brisbane, with the sole intention of visiting Steve Irwin's famous Australia Zoo... 

Steve Irwin was an absolute champion of his time, a legend in the world of conservation, animal welfare and life, and was just a character that was undeniably one of the best campaigners for animal rights the world has seen. Starting working in his families zoo in the 1980's he led it to a worldwide status that was held in high esteem - and all of the monies were ploughed back in to helping animals. This guy was a hero. So to visit his zoo was a dream come true, to see Steve there was beyond my expectations!

I had already learnt a lot about crocodiles and their behaviour from reading articles and seeing programmes from Steve, but to be there and learn from the master himself was awesome! He took to the central demo area (the crocoseum) with his wife Terri and team and taught us and showed us behaviours from the crocodiles that made you see them for the beautiful creatures they are. Yes they have big teeth and look scary, but looks can be deceiving,these guys have been around for centuries, they needed to be built hardy! It was just an amazing time, that involved chatting with Terri, cuddling a koala, and walking a wombat on a lead.  Most importantly, the chance to see one of my idols in action just blew me away, and inspired me to talk... what ever you are passionate about, and if you can help people see things in a less daunting and scary way, then do it.  

Perceptions are all very individual, but you can help widen them.

So thanks Nan and Granddad, you helped realise a dream even bigger than I had imagined.